Incredibly late thromboses in first generation drug eluting stents: a case series

نویسندگان

  • Zakir Shaik
  • Khaja S Mohammed
  • Adnan Siddiqi
  • Ilyas Mohammed
  • Timothy A Shapiro
  • Thomas P Phiambolis
چکیده

BACKGROUND The drug-eluting stents have decreased the incidence of instent restenosis compared to bare metal stents. But, the incidence of late and very late stent thrombosis has increased with the drug-eluting stents. CASE PRESENTATION We are here, reporting three cases of incredibly late instent thrombosis, each one occurring after more than 50 months of drug-eluting stent placement. CONCLUSION The occurrence of stent thrombosis as late as 5 years has been reported in literature. This highlights the importance that there may be no limit to the time duration to the occurrence of very late stent thrombosis and dual antiplatelet therapy with aspirin and clopidogrel may have to be continued indefinitely in patients with drug-eluting stents.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

[Very late taxus stent thrombosis and symptom-limited exercise testing].

At present, stent thromboses (ST) are relatively uncommon. Most occur within the first 24 hours (acute ST) or 1 to 30 days after implantation (subacute ST).1 In the case of bare-metal stents, late (>30 days) and very late (>1 year) thromboses are very rare. Drug-eluting stents considerably reduce restenosis and the need for new revascularizations2 and do not increase ST during the first year. H...

متن کامل

What to do about late incomplete stent apposition?

Acute and subacute stent thromboses have existed since the first stent implantation procedures. Initially recognized as a complication of brachytherapy, late stent thrombosis has become a public health issue only during the current era of drug-eluting stent (DES) implantation, as evidenced by the March 8, 2007, issue of the New England Journal of Medicine, which includes 5 articles, 2 perspecti...

متن کامل

Late and Very Late Stent Thrombosis in the Era of Second-generation Drug-eluting Stents

Stent thrombosis is a life-threatening complication of percutaneous coronary intervention that often results in ST-segment myocardial infarction or sudden cardiac death. First-generation drug-eluting stents (DESs) are associated with an increased risk of late and very late stent thrombosis compared with baremetal stents due to delayed endothelialisation of the stent struts. The second-generatio...

متن کامل

Zotarolimus - eluting versus sirolimus - eluting coronary stent implantation review

The safety and efficacy of coronary stents, utilized for treatment of ischemic heart disease, have been evaluated extensively. In comparison with bare-metal stents, first-generation drug-eluting stents more than halved the need for target lesion revascularization, but long-term safety has been questioned, as the first-generation drug-eluting stents seem to be associated with a small, but increa...

متن کامل

Late stent thrombosis after drug-eluting stent: seeing is understanding.

Following the inspiration of Dr S. Windecker, the team from Bern, Switzerland, has contributed 30 studies on drug-eluting stent efficacy and safety, several of which represent essential pieces in the puzzle. The article in this issue of Circulation by Cook et al1 belongs to that select group of key references. The series of robust and detailed reports on the Bern-Rotterdam cohort studies have c...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 2  شماره 

صفحات  -

تاریخ انتشار 2009